At Dr. Ozone Regenerative Medicine Clinic, we offer you Cord Blood Plasma IV, “Biological Gold.

What is Cord Blood Plasma and How is it Prepared?

Cord blood plasma is a vital substance collected immediately after a baby’s birth and the cutting of the umbilical cord, from the blood remaining in the cord and placenta. This moment is crucial because the blood contains a rare and rich concentration of stem cells, immune proteins, and this vital fluid is rich in growth factors, cytokines, structural proteins, and liquid stem cells (such as CD34+). It is considered one of the most powerful advancements in regenerative medicine globally.

Collection and Processing Steps:

1. Collection: The blood is drawn into sterile, anticoagulant-containing bags within minutes after cord clamping. It poses no harm to the mother or baby.

• Centrifugation: The sample is centrifuged to separate:

○ Plasma rich in proteins and growth factors

○ Blood cells

○ Liquid stem cells (e.g., CD34+)

• Processing: Plasma is purified to remove unwanted components while preserving its therapeutic integrity.

• Storage or Immediate Use: The plasma can be used fresh or cryopreserved at ultra-low temperatures for future use.

How Cord Blood Plasma Works Inside the Body

1. Bio-Distribution:

 After IV administration, growth factors, cytokines, and liquid stem cells circulate quickly to inflamed or damaged tissues. They target areas like the skin, joints, brain, and nerves.

• Cell Surface Binding and Signal Activation:

 Growth factors such as EGF, FGF, IGF-1, and VEGF bind to cell receptors and activate intracellular pathways:

• PI3K/Akt: promotes cell survival, growth, and angiogenesis ○ MAPK/ERK: stimulates cellular repair and division

• These signals travel to the nucleus, triggering gene expression for collagen synthesis, DNA repair, and tissue regeneration.

• Microenvironment Reprogramming:

 Cytokines like IL-10 and TGF-β reduce inflammation and shift the cellular state from “defense” to “repair,” creating an optimal healing environment.

• Endogenous Stem Cell Activation:

 CD34+ and progenitor cells in the plasma stimulate the body’s own stem cells (from bone marrow or fat) to migrate to injured areas, supporting angiogenesis, neurogenesis, and tissue repair.

• Improved Blood Flow and Oxygen Delivery:

 VEGF drives new blood vessel formation (neovascularization), increasing oxygen and nutrient delivery to cells.

• Immune Modulation:

 Immune activity is recalibrated through: ○ Balanced Th1/Th2 responses

• Activation of M2 macrophages

○ Reduction of inflammatory markers like TNF-α and IL-6

• Cellular and Functional Outcomes:

• Increased collagen and improved skin structure

○ Enhanced neuroregeneration, focus, and memory

○ Reduced joint pain and better mobility

○ Stronger immune system and overall vitality

○ Boosted hormonal and sexual wellness

Timing of Benefits

• Immediate (24–48 hours): noticeable energy and mental clarity
• Short-term (weeks): visible skin improvements, deeper healing
• Long-term: ongoing regeneration due to stem cell activation and restored cell environments

Why Cord Blood Plasma Is Unique in Regenerative Medicine

Cord blood plasma offers a rich concentration of:

• Growth factors (EGF, FGF, IGF, VEGF)
• Immunomodulatory cytokines (IL-10, TGF-β)
• Immune proteins and structural molecules (albumin, fibronectin)
• Liquid stem cells (CD34+)

 These components help reset the biological system at the cellular level.

Medical and Regenerative Uses:

• Nervous System:

Supports recovery after strokes or brain injuries.

Improves focus, memory, and cognitive functions.

• Musculoskeletal System:

Accelerates the healing of muscle injuries.

Supports joints and bones, reducing chronic pain.

• Skin and Anti-Aging:

Regenerates skin cells from within.

Naturally reduces wrinkles and fine lines.

• Sexual Functions:

Boosts sexual health in both men and women.

Supports hormonal function and blood flow to reproductive organs.

• Overall Recovery and Energy Regeneration:

Ideal for those suffering from chronic fatigue, weakened immunity, or a general decline in vitality.

Summary Cord Blood Plasma IV therapy is a scientifically backed regenerative solution that triggers a cascade of biological repair processes. From receptor activation to gene expression and immune recalibration, this therapy offers long-term rejuvenation from within.